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鍞悗鏈嶅嫏(w霉)
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鎷滆惉(w脿n)鎴堬紙鐟炴垐闈炲凹鐗囷級閬╃敤浜庢不鐧傛棦寰€鎺ュ彈閬�(gu貌)浠ユ盁灏垮槯鍟躲€佸ェ娌欏埄閴戝拰浼婄珛鏇垮悍鐐哄熀绀�(ch菙)鐨勫寲鐧�锛屼互鍙婃棦寰€鎺ュ彈閬�(gu貌)鎴栦笉閬╁悎鎺ュ彈鎶梀EGF娌荤檪銆佹姉EGFR娌荤檪(RAS閲庣敓鍨�)鐨勮綁(zhu菐n)绉绘€х祼(ji茅)鐩磋吀鐦�(mCRC)鎮ｈ€�?锛涢鍜傜秿r(sh铆)鍙互澶氶€�(j矛n)琛岃壘鐏�銆佹帹鎷�銆佹寜鎽╃瓑鐗╃悊娌荤檪锛岃兘澶犱績閫�(j矛n)琛€娑插惊鐠�(hu谩n)銆� 瑭虫儏
娼為花鍙冨彛鏈嶆恫鍔熻兘涓绘不:瑁�(b菙)涓泭姘ｏ紝鍋ヨ劸鐩婅偤锛屾粙瑁�(b菙)寮�(qi谩ng)澹�锛屽寮�(qi谩ng)浜洪珨鍏嶇柅鑳藉姏銆傜敤浜庤劸鑲鸿櫅寮�锛屾埃鐭績鎮�锛岄灏戜究婧�锛岃櫅鍠樺挸鍡姐€傞€欐槸涓€绋彛鏈嶈棩鐗�锛屽畠鐨勫彛鏈嶇敤閲忔槸涓€澶╃敤钘ュ叐娆★紝涓€娆℃湇鐢�10姣崌锛屽悇浣嶈娉ㄦ剰鎸夎(gu墨)瀹氫娇鐢�銆� 瑭虫儏
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鎷滆惉(w脿n)鎴堥仼鐢ㄤ簬娌荤檪鏃㈠線鎺ュ彈閬�(gu貌)浠ユ盁灏垮槯鍟�銆佸ェ娌欏埄閴戝拰浼婄珛鏇垮悍鐐哄熀绀�(ch菙)鐨勫寲鐧�锛屼互鍙婃棦寰€鎺ュ彈閬�(gu貌)鎴栦笉閬╁悎鎺ュ彈鎶梀EGF娌荤檪銆佹姉EGFR娌荤檪锛圧AS閲庣敓鍨嬶級鐨勮綁(zhu菐n)绉绘€х祼(ji茅)鑵哥檶锛坢CRC)鎮ｈ€呫€� 瑭虫儏
娼為花鍙冨彛鏈嶆恫鐢ㄤ簬鑴捐偤铏涘急锛屾埃鐭績鎮�锛岄灏戜究婧�锛岃櫅鍠樺挸鍡�锛涗富娌昏劸铏涘瀷灏忓厭娉勭€夛紝濠︾敘(ch菐n)绉戣钵琛€锛屾參鎬ц儍鐐�锛屾參鎬ц厧鐐庡強鏀惧寲鐧傚悗鑴捐偤姘ｈ櫅璜哥櫏銆傛湰鍝佹噳(y墨ng)瑭插湪瀵嗗皝鐨勬浠朵笅淇濆瓨锛屼繚璩�(zh矛)鏈熸槸涓夊勾锛屾不鐧傛湡闁撶殑绂佸繉灏氫笉鏄庣⒑銆� 瑭虫儏
娼為花鍙冨彛鏈嶆恫浣跨敤鏂规硶鐐哄彛鏈�锛屾瘡涓€娆￠渶瑕佷娇鐢�10姣崌锛屼竴鏃ュ彲浣跨敤鍏╂銆傚厭绔ユ噳(y墨ng)瑭茶鍦ㄩ啱(y墨)鐢熺殑鎸囧皫(d菐o)涓嬮厡鎯呮笡灏戠敤閲忔垨浣跨敤闋荤巼銆傛湰鍝佺敤浜庤劸鑲鸿櫅寮�锛屾埃鐭績鎮�锛岄灏戜究婧忥紝铏涘枠鍜冲椊锛涗富娌昏劸铏涘瀷灏忓厭娉勭€�锛屽│鐢�(ch菐n)绉戣钵琛€锛屾參鎬ц儍鐐�锛屾參鎬ц厧鐐庡強鏀惧寲鐧傚悗鑴捐偤姘ｈ櫅璜哥櫏銆� 瑭虫儏
璨濅紣鐝犲柈鎶楁敞灏勬恫鐐洪潨鑴堟敞灏勭敤鐒�(w煤)鑿屾憾娑�锛宲H5.9~6.3锛屾緞娓呰嚦寰付涔冲厜銆佺劇(w煤)鑹茶嚦娣烘鑹叉恫楂�銆傝矟浼愮彔鍠姉娉ㄥ皠娑插姂閲�銆佺郸钘ユ柟寮忓強鐧傜▼鍧囬渶鍤�(y谩n)鏍兼寜鐓ч啱(y墨)鐢熻檿鏂瑰煼(zh铆)琛�锛屼笉鍙嚜琛屽娓涙垨涓柗娌荤檪锛屼互鍏嶅奖闊跨檪鏁堟垨澧炲姞涓嶈壇鍙嶆噳(y墨ng)棰�(f膿ng)闅�(xi菐n)銆� 瑭虫儏
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姝ｄ締(l谩i)娼為花娼為花鍙冨湪閱�(y墨)闄㈢殑鍍�(ji脿)鏍肩┅(w臎n)瀹氾紝鍦ㄩ€ｉ帠钘ユ埧鐨勫児(ji脿)鏍肩浉灏�(du矛)渚垮疁涓€榛�(di菐n)锛屼絾鏄噳(y墨ng)瑭蹭互瀵�(sh铆)闅涗簡瑙ｅ埌鐨勫児(ji脿)鏍肩偤婧�(zh菙n)銆傛偅鑰呮噳(y墨ng)瑭茶娉ㄦ剰闁辫畝瑾�(shu艒)鏄庢浉鍏�(n猫i)瀹�锛屼竴鑸彲鐭ラ亾鏈棩鍝佸彲瑁�(b菙)涓泭姘�锛屽仴鑴剧泭鑲�锛屾粙瑁�(b菙)寮�(qi谩ng)澹�锛屽寮�(qi谩ng)浜洪珨鍏嶇柅鑳藉姏銆� 瑭虫儏
姝ｄ締(l谩i)娼為花娼為花鍙冨彲瑁�(b菙)涓泭姘�锛屽仴鑴剧泭鑲�锛屾粙瑁�(b菙)寮�(qi谩ng)澹紝澧炲挤(qi谩ng)浜洪珨鍏嶇柅鑳藉姏锛屼繚璩�(zh矛)鏈熸槸涓夊勾锛屽鏋滃瓨鍦ㄤ繚瀛樹笉鎭扮暥(d膩ng)?sh霉)閭ｉ梿r锛屽氨瀹规槗鎻愬墠璁婅唱(zh矛)銆傚叾娆�锛屾偅鑰呰閬告搰姝ｈ(gu墨)鐨勬笭閬撹臣(g貌u)璨疯棩鐗�锛岄渶瑕佷粩绱�(x矛)鐨勫幓浜嗚В璀�(h霉)鐞嗗伐浣滃拰娉ㄦ剰浜嬮爡(xi脿ng)銆� 瑭虫儏
姝ｄ締(l谩i)娼為花娼為花鍙冨彲瑁�(b菙)涓泭姘ｏ紝鍋ヨ劸鐩婅偤锛屾粙瑁�(b菙)寮�(qi谩ng)澹紝澧炲挤(qi谩ng)浜洪珨鍏嶇柅鑳藉姏锛屽湪閱�(y墨)闄㈠拰钘ュ簵鐨勫児(ji脿)鏍煎苟涓嶇浉鍚�锛岀附楂旂殑宸窛骞朵笉澶�锛岄¨瀹㈠彲浠ュ埌鍏烽珨鐨勫湴鏂逛簡瑙ｄ竴涓嬨€傚叾娆℃噳(y墨ng)瑭茶鑰愬績鐨勫仛濂借(h霉)鐞嗗伐浣�锛岀⿳妤电殑鍘讳簡瑙ｇ敤钘ユ柟妗堛€� 瑭虫儏
姝ｄ締(l谩i)娼為花娼為花鍙冮渶瑕佹寜鐓ц(gu墨)瀹氱殑瑕佹眰浣跨敤锛屼絾鏄湪瑾�(shu艒)鏄庢浉閲岄潰骞舵矑(m茅i)鏈変粙绱圭檪绋嬩俊鎭紝鍥犳鍙牴鎿�(j霉)鍊�(g猫)浜烘儏娉佷締(l谩i)鍏烽珨瀹夋帓銆傛湰鍝佸彲瑁�(b菙)涓泭姘�锛屽仴鑴剧泭鑲�锛屾粙瑁�(b菙)寮�(qi谩ng)澹�锛屽寮�(qi谩ng)浜洪珨鍏嶇柅鑳藉姏銆� 瑭虫儏
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娼為花鍙冨彛鏈嶆恫淇濊唱(zh矛)鏈熸槸36骞�锛屾噳(y墨ng)瑭插湪瀵嗗皝鐨勬浠朵笅淇濆瓨锛岄渶瑕佹斁鍦ㄩ櫚娑煎共鐕ヨ檿銆傛湰鍝佺敤浜庤劸鑲鸿櫅寮憋紝姘ｇ煭蹇冩偢锛岄灏戜究婧忥紝铏涘枠鍜冲椊锛涗富娌昏劸铏涘瀷灏忓厭娉勭€�锛屽│鐢�(ch菐n)绉戣钵琛€锛屾參鎬ц儍鐐�锛屾參鎬ц厧鐐庡強鏀惧寲鐧傚悗鑴捐偤姘ｈ櫅璜哥櫏銆� 瑭虫儏
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