璩�(g貌u)鐗╂寚鍗�
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鏀粯鏂瑰紡
閰嶉€佹湇鍕�(w霉)
鍞悗鏈嶅嫏(w霉)
闂�(gu膩n)浜庢垜鍊�
姘熶粬鑳虹墖鐢ㄦ硶鐢ㄩ噺锛氭瘡娆�0.25g锛堜竴鐗囷級锛屽彛鏈�锛屾瘡鏃�3娆�銆傛盁浠栬兒鐗囪棩鐞嗘瘨鐞嗭細鏈搧鐐洪潪椤炲浐閱囩殑闆勬縺绱犳嫯鎶楀姂锛岃垏闆勬縺绱犵(j矛ng)鐖�(zh膿ng)鑵槫閮ㄤ綅鐨勯泟婵€绱犲彈楂�銆傛偅鑰呰鍋氬ソ鐤剧梾鐨勭洠(ji膩n)娓�(c猫)锛岀暀鎰忔偅鑰呯殑韬珨璁婂寲锛岃嫢鏈夌暟甯歌鍙婃檪(sh铆)鐨勫弽楗嬬郸閱�(y墨)鐢燂紝鍚屾檪(sh铆)涔熻鍔犲挤(qi谩ng)鐕�(y铆ng)椁�(y菐ng)鐨勪緵绲�銆� 瑭虫儏
姘熶粬鑳虹墖瑾�(shu艒)鏄庢浉娉ㄦ剰浜嬮爡(xi脿ng)锛氶渶闀�(zh菐ng)鏈熸湇鐢ㄦ湰鍝佹檪(sh铆)鎳�(y墨ng)瀹氭湡妾㈡煡鑲濆姛鑳藉拰绮惧瓙瑷�(j矛)鏁�(sh霉)锛屽鐧�(f膩)鐢熺暟甯告噳(y墨ng)娓涢噺鎴栧仠钘ワ紝涓€鑸彲鎭㈠京(f霉)姝ｅ父銆傛偅鑰呭钩鏅�(sh铆)瑕佹敞鎰忓€�(g猫)浜虹殑琛�(w猫i)鐢熷伐浣�锛屼繚鎸佺敓娈栧強閮ㄤ綅鐨勬竻娼�锛岄厤鍋惰鍋氬ソ闄伴儴鐨勮(w猫i)鐢�锛岄槻姝㈢窗(x矛)鑿岄€�(j矛n)鍏ョ敺鎬ч櫚閬�锛屽缓璀版瘡澶╃敤婧按閫�(j矛n)琛屾竻娲�銆� 瑭虫儏
鍓嶅垪鑵虹檶鏄敺绉戠梾鐧ョ暥(d膩ng)涓殑涓€绋紝鍑虹従(xi脿n)鐨勫彲鑳芥€х浉灏�(du矛)杓冨ぇ锛岄渶瑕佹偅鑰呭強鏅�(sh铆)鐨勯€�(j矛n)琛屾不鐧傛噳(y墨ng)灏�(du矛)銆傝€屾盁浠栬兒鐗囬仼鐢ㄤ簬鍓嶅垪鑵虹檶锛屽皪(du矛)鍒濇不鍙婂京(f霉)娌绘偅鑰呴兘鍙湁鏁�锛涜€岃棩鐗╃殑涓嶈壇鍙嶆噳(y墨ng)锛氱敺鎬т钩鎴垮コ鎬у寲锛屼钩鎴胯Ц鐥�锛屾湁鏅�(sh铆)浼存湁婧钩锛涘娓涘皯鍔戦噺鎴栧仠钘ュ墖鍙秷澶�锛涘皯鏁�(sh霉)鎮ｈ€呭彲鏈夎吂鐎�銆佹儭蹇冦€佸様鍚�銆侀娆插鍔�銆佸け鐪犲拰鐤插嫗锛涚綍瑕嬫€ф娓涗綆銆佷竴閬�(gu貌)鎬ц倽鍔熻兘鐣板父鍙婄簿瀛愯▓(j矛)鏁�(sh霉)娓涘皯锛涙湰鍝佸皪(du矛)蹇冭绠＄殑娼涘湪鎬у奖闊挎瘮宸辩儻闆岀浖灏�銆� 瑭虫儏
搴峰＋寰楄垏淇冮粌楂旂敓鎴愮礌閲嬫斁婵€绱�(LHRH)椤炰技鐗╂垨澶栫鐫父鍒囬櫎琛�(sh霉)鑱�(li谩n)鍚堟噳(y墨ng)鐢ㄤ簬鏅氭湡鍓嶅垪鑵虹檶鐨勬不鐧傘€傜洰鍓�锛岃棩鐗╃殑鍞児(ji脿)鐩稿皪(du矛)杓冮珮锛屼絾鏄篃鏈夋尝鍕�(d貌ng)锛屽彲浠ュ埌閱�(y墨)闄㈡垨鑰呮槸钘ユ埧鍜ㄨ浜嗚В钘ョ墿鐨勫児(ji脿)鏍�锛屽钩鏅�(sh铆)涔熷彲浠ュ幓浜嗚В鐣�(d膩ng)?sh霉)姘愬凹t(y墨)淇濇斂绛�锛岀鍚堟浠剁殑鑳藉鍫�(b脿o)閵烽啱(y墨)淇濇笡杓曞搴稉(j墨ng)婵�(j矛)璨�(f霉)鎿�(d膩n)銆� 瑭虫儏
鍚勫ぇ钘ユ埧閮芥湁姣斿崱榄兒鐗囧嚭鍞�锛屽叾鐢ㄦ硶鐢ㄩ噺锛氭垚浜猴細鎴愬勾鐢锋€у寘鎷€佸勾浜猴細涓€鐗�(50mg)锛屼竴澶╀竴娆�锛岀敤搴峰＋寰楁不鐧傛噳(y墨ng)鑸嘗HRH椤炰技鐗╂垨澶栫鐫父鍒囬櫎琛�(sh霉)娌荤檪鍚屾檪(sh铆)闁嬪锛涘厭绔ワ細鏈搧绂佺敤浜庡厭绔ワ紱鑵庢悕瀹筹細灏�(du矛)浜庤厧鎼嶅鐨勭梾浜虹劇(w煤)闇€瑾�(di脿o)鏁村姂閲�锛涜倽鎼嶅锛氬皪(du矛)浜庤紩搴﹁倽鎼嶅鐨勭梾浜虹劇(w煤)闇€瑾�(di脿o)鏁村姂閲忥紝涓噸搴﹁倽鎼嶅偡鐨勭梾浜哄彲鑳界櫦(f膩)鐢熻棩鐗╄搫绌�(瑕嬫敞鎰忎簨闋�(xi脿ng))銆� 瑭虫儏
姘熶粬鑳虹墖瑾�(shu艒)鏄庢浉涓嶈壇鍙嶆噳(y墨ng)锛氱敺鎬т钩鎴垮コ鎬у寲锛屼钩鎴胯Ц鐥�锛屾湁鏅�(sh铆)浼存湁婧钩銆傚娓涘皯鍔戦噺鎴栧仠钘ュ墖鍙秷澶�銆傚皯鏁�(sh霉)鎮ｈ€呭彲鏈夎吂鐎�銆佹儭蹇�銆佸様鍚愩€侀娆插鍔�銆佸け鐪犲拰鐤插嫗銆傛偅鑰呭湪鎮ｇ梾鍚庨渶瑕佸湪閱�(y墨)鐢熺殑鎸囧皫(d菐o)涓嬮€�(j矛n)琛屾不鐧�锛屾棩甯镐篃瑕佸姞寮�(qi谩ng)鍋氬ソ瑾�(di脿o)鐞嗭紝骞虫檪(sh铆)瑕佹敞鎰忛伩鍏嶆唻灏�銆� 瑭虫儏
钘ョ墿閮芥渻(hu矛)瀛樺湪鐩镐簰浣滅敤锛岃€屾盁浠栬兒鐗囪棩鐗╃浉浜掍綔鐢ㄦ槸灏氫笉鏄庣⒑銆傚悓鏅�(sh铆)锛屽悎骞剁敤鍏朵粬钘ョ墿鏅�(sh铆)锛屾噳(y墨ng)娉ㄦ剰钘ョ墿闁撶殑鐩镐簰浣滅敤锛屽挨鍏舵槸鍦ㄤ娇鐢ㄦ姉鐢熺礌銆佹姉鍑濊棩鎴栧叾浠栧奖闊挎縺绱犳按骞崇殑钘ョ墿鏅�(sh铆)锛屽垏鍕块毃鎰忛厤浼�锛岄渶鍜ㄨ閱�(y墨)甯剰瑕�銆傛澶�锛屽墠鍒楄吅鐧岀殑娌荤檪閫氬父闇€瑕佽純闀�(zh菐ng)鏅�(sh铆)闁�锛屾偅鑰呴渶淇濇寔鑰愬績鍜屼俊蹇�锛屽垏鍕垮崐閫旇€屽虎銆� 瑭虫儏
姘熶粬鑳虹墖涓嶈壇鍙嶆噳(y墨ng)锛氱敺鎬т钩鎴垮コ鎬у寲锛屼钩鎴胯Ц鐥�锛屾湁鏅�(sh铆)浼存湁婧钩锛涘娓涘皯鍔戦噺鎴栧仠钘ュ墖鍙秷澶�锛涘皯鏁�(sh霉)鎮ｈ€呭彲鏈夎吂鐎夈€佹儭蹇�銆佸様鍚愩€侀娆插鍔犮€佸け鐪犲拰鐤插嫗锛涚綍瑕嬫€ф娓涗綆銆佷竴閬�(gu貌)鎬ц倽鍔熻兘鐣板父鍙婄簿瀛愯▓(j矛)鏁�(sh霉)娓涘皯銆傛湰鍝佸皪(du矛)蹇冭绠＄殑娼涘湪鎬у奖闊挎瘮宸辩儻闆岀浖灏忋€� 瑭虫儏
涓嶅悓鐨勬偅鑰呯梾鎯呯殑鐧�(f膩)灞曟儏娉佷互鍙婂皪(du矛)浜庤棩鐗╃殑鍚告敹鏄笉涓€妯ｇ殑锛岄偅涔堟湇鐢ㄨ棩鐗╃殑鏅�(sh铆)闁撲篃涓嶅悓锛岃兘鍚﹂暦(zh菐ng)鏅�(sh铆)闁撶殑鏈嶇敤钘ョ墿闇€瑕佸挩瑭㈤啱(y墨)鐢熴€傛盁浠栬兒鐗囬仼鐢ㄤ簬鍓嶅垪鑵虹檶锛屽皪(du矛)鍒濇不鍙婂京(f霉)娌绘偅鑰呴兘鍙湁鏁�锛涜€岃(shu艒)鏄庢浉鐢ㄦ硶鐢ㄩ噺锛氭瘡娆�0.25g锛堜竴鐗囷級锛屽彛鏈�锛屾瘡鏃�3娆�銆� 瑭虫儏
鐢熻瀵х墖鐩婃埃瑁�(b菙)琛€锛岀敤浜庣己閻垫€ц钵琛€灞埃琛€鍏╄櫅璀夎€咃紝璀夎锛氶潰閮�銆佽倢鑶氳悗榛冩垨钂肩櫧锛岀鐤蹭箯鍔�锛岀湬鏆堣€抽炒锛屽績鎮告埃鐭�锛岃垖娣℃垨鑳�锛岃剤寮辩瓑锛涘叾娆�锛岃(shu艒)鏄庢浉涓嶈壇鍙嶆噳(y墨ng)锛氬皯鏁�(sh霉)鎮ｈ€呯敤钘ュ悗鍙涓婅吂涓嶉仼锛屾儭蹇�锛涘€�(g猫)鍒ユ偅鑰呭ぇ渚挎鏁�(sh霉)澧炲锛涘嚭鐝�(xi脿n)鐨柟锛涘彟澶�锛屾湁鍊�(g猫)鍒ョ梾渚嬬敤钘ュ悗鍑虹従(xi脿n)涓€х矑绱�(x矛)鑳炵暟甯�锛屾湭鑳借偗瀹氳垏鏈嶇敤鐢熻瀵х墖鏈夐棞(gu膩n)銆� 瑭虫儏
瑗胯棌鐢橀湶钘忚棩鑲′唤鏈夐檺鍏徃鏄簩鍗佷簲鍛宠偤鐥呬父鐨勭敓鐢�(ch菐n)寤犲锛屽叾鎴愪唤锛氭獉棣欍€佹嚫閴ゆ湪銆佺煶鐏拌彲銆佸北鏌�銆佺磪鑺便€佽憽钀�銆佺崘鐗欒彍銆佺敇鑽�銆佸厰鑰宠崏銆佹矙妫樿啅銆佸反澶忓槑銆侀鏃辫姽銆佹鍢�銆佺櫧鑺遍緧鑶�銆佽ǘ瀛�銆佽倝鏋滆崏銆佹瘺瑷跺瓙銆佺劇(w煤)鑾栬姤銆佷綑鐢樺瓙銆佺敇鑲呰殼缍�銆佽棌鏈ㄩ銆侀惖妫掗寴(鏍�銆佽憠)銆佸绛嬭棨銆佷汉宸ョ墰榛冦€佸姏鍢庨兘銆� 瑭虫儏
钘ュ児(ji脿)瀛樺湪鏈夎畩鍕�(d貌ng)锛屽児(ji脿)鏍兼儏娉佽浠ョ暥(d膩ng)澶╃殑鍜ㄨ?y艒u)闂�?zh菙n)銆傜茎鍩鸿劜鐗囧皪(du矛)鎱㈡€х矑绱�(x矛)鑳炵櫧琛€鐥咃紙CML锛夋湁鏁�锛屽苟鍙敤浜庡皪(du矛)棣埄铇€愯棩鐨凜ML锛涘叾娆�锛屽皪(du矛)榛戣壊绱犵槫銆佽厧鐧�銆侀牠闋搁儴鐧屾湁涓€瀹氱檪鏁�锛岃垏鏀剧檪鑱�(li谩n)鍚堝皪(du矛)闋牳閮ㄥ強瀹牳楸楃檶鏈夋晥銆傝棩鐗╁瓨鍦ㄦ湁绂佸繉锛屼竴鑸� 姘寸棙銆佸付鐙€鐨扮柟鎮ｈ€呮槸涓嶅彲浠ヤ娇鐢ㄩ€欎竴钘ョ墿鐨�锛屽彟澶栧瓨鍦ㄦ湁鍚勭ó鍤�(y谩n)閲嶆劅鏌撲篃瑕佺鐢ㄣ€� 瑭虫儏
钘ョ墿涓嶈兘閬�(gu貌)閲忎娇鐢�锛岃€屾盁浠栬兒鐗囪棩鐗╅亷(gu貌)閲忔槸灏氫笉鏄庣⒑銆傚績鐞嗚(h霉)鐞嗕篃鏄墠鍒楄吅鐧屾偅鑰呰(h霉)鐞嗕腑涓嶅彲蹇借鐨勪竴鐠�(hu谩n)銆傜檶鐧ョ殑瑷烘柗寰€寰€鏈�(hu矛)绲︽偅鑰呭績鐞嗕笂甯朵締(l谩i)妤靛ぇ鐨勫鍔�锛屽洜姝�锛屾彁渚涚⿳妤电殑蹇冪悊鏀寔椤緱灏ょ偤閲嶈銆傛偅鑰呭強瀹跺爆鍙互閫氶亷(gu貌)鍙冨姞鐩搁棞(gu膩n)鐨勬敮鎸佸皬绲�锛岃垏鍏朵粬鎮ｈ€呭垎浜稉(j墨ng)椹�(y脿n)鍜屾劅鍙�锛屽公鍔╁郊姝ら潰灏�(du矛)鐤剧梾銆� 瑭虫儏
姘熶粬鑳虹墖瑾�(shu艒)鏄庢浉涓嶈壇鍙嶆噳(y墨ng)锛氱敺鎬т钩鎴垮コ鎬у寲锛屼钩鎴胯Ц鐥�锛屾湁鏅�(sh铆)浼存湁婧钩銆傚娓涘皯鍔戦噺鎴栧仠钘ュ墖鍙秷澶�銆傚皯鏁�(sh霉)鎮ｈ€呭彲鏈夎吂鐎�銆佹儭蹇�銆佸様鍚�銆侀娆插鍔犮€佸け鐪犲拰鐤插嫗?锛涢鍜€垛拋鐛楋紦璀匢(y铆ng)椁�(y菐ng)鍧囪 锛屽鍚冨瘜鍚董鐢熺礌鍜岀う鐗╄唱(zh矛)鐨勯鐗╋紝澶氬悆钄彍鍜屾按鏋�锛岄伩鍏嶉鐢ㄩ珮鑴傝偑銆侀珮鐔遍噺鐨勯鐗┿€� 瑭虫儏
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